RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
mir-143
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
dual-luciferase reporter assay
Target
SPRY3
Pathway
MAPK SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-143-3p promotes human cardiac fibrosis via targeting sprouty3 after myocardial infarction
Year
2019
Function
"miR-143-3p promoted fibrosis along with SPRY3 degradation and the activation of its downstream p38, ERK, and JNK pathways."